Scientist/Senior Scientist. Biology
Your Purpose:
Alpha-9 Oncology is seeking a highly motivated Scientist or Senior Scientist to join our Biology group in our growing organization. The ideal candidate will bring deep expertise in Cancer, Molecular/Cell Biology, Biochemistry, and/or Pharmacology, with hands-on experience in in vitro assay development for drug design. Industry experience is required, and experience with radiopharmaceutical development is a plus.
Reporting to the Associate Director, Biology, you will play a crucial role in advancing our pipeline by designing, validating, and executing preclinical experiments to assess the activity and mechanism of action of drug candidates. You’ll contribute to key in vitro research efforts, collaborate with cross-functional teams, and have the opportunity to lead a team of junior scientists in a fast-paced, innovative environment.
What You’ll Do:
- Lead, manage and execute experiments to validate pipeline targets.
- Contribute to the in vitro expertise across pipeline targets
- Design, validate and execute preclinical experiments to demonstrate in vitro activities as well as define mechanism of action of drug candidates.
- Contribute to strategic plans and assays development.
- Expertise in cell culture and in vitro assays to validate targets, screen drug candidates and determine MoA
- Experience with target expression validation (e.g. flow cytometry, ELISA, western blot), andmolecular biology techniques (e.g., qPCR, cloning)
- Interpret and analyze data, prepare, and review study reports, communicate project progress to internal team members and external collaborators.
- Supervise and mentor junior staffs including Associate Scientists
- Assist with lab management tasks such as lab safety advisory, lab inspections and inventories.
- Perform other related duties within the Biology group as needed.
What You’ll Bring:
- A PhD in Cancer, Cell or Molecular Biology, Biochemistry, and/or Pharmacology with 2-5+ years of relevant post-doctoral training or industrial experience and a proven track record of scientific excellence and creativity
- Expertise in the development, optimization and execution of assays to establish MoA, binding affinity, selectivity and potency.
- Experience in radiopharmaceutical discovery preferred but not required.
- Excellent observational, organizational, data management, and documentation skills
- A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies in a fast-paced start-up environment
What’s in it for you:
At Alpha-9 Oncology, we offer a competitive and comprehensive benefits package designed to support all employees. Our benefits include a competitive salary, bonus, equity, 20 vacation days, 5 sick days, a technology allowance, and commuter reimbursement. We also provide generous retirement savings plans with employer matching, extended health benefits, and paid holidays, tailored to local standards in each region. While specific offerings may vary by location, our commitment to fostering a supportive and rewarding work environment is consistent across the company.
Company Summary
Alpha-9 Oncology is a clinical-stage biotechnology company developing radiopharmaceuticals for solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. With a strong cash position, raised from leading healthcare investors, Alpha-9 is poised to dramatically expand its team and accelerate its pipeline.
Radiopharmaceuticals, which enable internal delivery of radiation directly to tumor sites, are emerging as an exciting new class of cancer drugs. The field has evolved dramatically in the last few years, attributable to scientific advances and recent product launches. Radiopharmaceuticals are unique in that the same molecule can be used for imaging or therapeutic purposes, allowing doctors to visualize the molecule in patients prior to administration of therapy. The drug development cycle is also much shorter and capital efficient than traditional modalities.
More about Alpha-9 Oncology
Alpha-9 Oncology is committed to fostering a diverse and inclusive workplace and is proud to be an Equal Opportunity Employer. We provide employment opportunities to all qualified applicants without regard to race, ethnicity, religion, age, sex, gender identity or expression, sexual orientation, disability, marital status, family status, national origin, or any other characteristic protected by applicable federal, provincial, or local laws where we operate.
We are dedicated to providing reasonable accommodations to qualified applicants and employees to ensure that everyone can perform their essential job functions in an inclusive environment. For inquiries regarding accommodations in the hiring process or for current employees, please contact a member from our Talent Acquisition team.
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